London Irish's number eight Phil Murphy will make his 134th and final appearance for the club against Sale.
The Canadian international starts at Edgeley Park on Saturday and told BBC Radio Berkshire it will be emotional.
Murphy will join Italian side Viadana and said he would miss the London Irish supporters in particular.
He said: "What a great bunch of people - they'll always be close to me and to my family and I will always have London Irish in my thoughts."
Murphy made his final home appearance last Sunday as Irish beat Leeds in Reading and he said he was overwhelmed by the support he received.
"I was in shock and awe of the fans - there was a good four or five thousand fans who stayed around for the presentation."
"In Italy we have a little bit more time off and it only costs a tenner to fly from Parma to Stansted so I'll definitely be coming over for the big games"
Murphy has spent five years at Irish since joining from French side Perpignan. He believes he is leaving a better club than the one he joined.
"London Irish used to give people a good game, but it was all about the craic," he said.
"We still do enjoy each others company and go out for evenings of fun, but this year was much more about the business side of things - getting things right out on the field and it paid dividends.
"We're in the best shape we've been in for the past five years."
Although Murphy is sad to be leaving the Exiles, he said the timing was right for him and there are no regrets.
"Whenever you leave a club, you don't want it to be on bad terms because I have so many good memories, I don't want anything to spoil it," he said.
"Brian Smith was very honest with me and I was with him.
"Viadana are trying to do something special next year and have made some big signings and they have a very forward-thinking coach.
"I'm really looking forward to the challenge and this next stage of my career.
"It would have been a bit different if I was planning to spend my life here - I would have been looking for another Premiership club and to settle down.
"But I know I'm going back to Canada when I'm finished playing, so it's a great time to move on and experience a different culture, a new way of life and a different language."
Murphy warns London Irish supporters that they may not have seen the back of him yet.
He said: "In Italy we have a little bit more time off and it only costs a tenner to fly from Parma to Stansted so I'll definitely be coming over for the big games.
"When I first came here from the beautiful south of France, I did wonder what I had done. But no regrets whatsoever.
"It's been a fantastic five years and I'll always be London Irish through and through."
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